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Br512: an improved DNA polymerase for isothermal amplification assays
Unmet need Loop-mediated isothermal amplification (LAMP) is a technique that allows for nucleic acid amplification without the need for a thermocycler. This technology enables testing for infections practically anywhere. Testing shortages have exacerbated the COVID-19 pandemic, and there is a high demand for tests that can provide rapid results outside...
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Potent broad-spectrum antiviral for COVID-19 treatment
Unmet need Broad-spectrum antiviral drugs like remdisivir and niclosamide are promising treatments for COVID-19. Multiple clinical studies of remdisivir have shown benefits such as reduced recovery time. However, in November of 2020 the WHO recommended against the use of remdisivir for COVID-19 treatment based on questions of effectiveness. There remains...
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Sensitivity enhancement for diagnostic assays
Problem The COVID-19 pandemic has ushered in a new era of diagnostic testing. Patients now demand rapid results, and they want testing to happen in a safe and convenient setting. Regulatory agencies and the biotech industry are working together to meet this need. Fierce competition is emerging among the hundreds of tests that have now received Emergency...
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