Andrew Ellington

Technologies

• Br512: an improved DNA polymerase for isothermal amplification assays
• Bacterial reagents: stable, low-cost, readily available reagents with no purification requirements
• Predicting off-target activity of CRISPR-Cas9 complexes
• An engineered methyltransferase enzyme for improved production of benzylisoquinoline alkaloids
• Engineered methyltransferase for microbial production of the Alzheimer’s drug galantamine
• Plastic-degrading enzymes
• Revolutionizing plastic recycling: FAST-PETase enzyme variant
• Thermostable reverse transcriptase based on a thermostable DNA polymerase
• Innovative modularization of One Pot PURE system for commercial unnatural amino acid incorporation
• Low-cost rapid diagnosis of viral diseases
• Engineered RNA polymerases and capping enzymes for the expression of 7‑methylguanylate capped RNA
• Unbiased material identification and characterization using proximity ligation assay technology
• SmartScreen: enhancing receptor interactions with RCPR technology
• Chemical language model for identifying functionally similar molecules across structural variants