Andrew Ellington

Technologies

• Br512: an improved DNA polymerase for isothermal amplification assays
• Bacterial reagents: stable, low-cost, readily available reagents with no purification requirements
• An engineered methyltransferase enzyme for improved production of benzylisoquinoline alkaloids
• Engineered methyltransferase for microbial production of the Alzheimer’s drug galantamine
• Plastic-degrading enzymes
• Revolutionizing plastic recycling: FAST-PETase enzyme variant
• Thermostable reverse transcriptase based on a thermostable DNA polymerase (RTX)
• Low-cost rapid diagnosis of viral diseases
• Engineered RNA polymerases and capping enzymes for the expression of 7‑methylguanylate capped RNA
• Unbiased material identification and characterization using proximity ligation assay technology
• SmartScreen: enhancing receptor interactions with RCPR technology
• Universal chimeric primer system for real-time, sequencing-compatible lamp assays
• Engineered bacterial platform for in situ mRNA delivery to mammalian cells
• Engineered E. coli platform for high-yield selenoprotein expression
• Engineered orthogonal elongation factor for SECIS-independent noncanonical amino acid incorporation
• Sequence-defined oligourethane probe libraries for high-resolution surface characterization
• Supercharged fluorescent protein biosensors for real-time lanthanide monitoring
• Allosteric transcription factors as peptide sensors
• Genetically engineered cell surface biosensors for high-throughput detection, screening, and recovery of rare earth elements