Search results for isothermal+amplification

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Bacterial reagents: stable, low-cost, readily available reagents with no purification requirements

Problem Most molecular biology techniques commonly used in research, biotechnology, healthcare, and education rely heavily on purified functional protein reagents. However, purification of these protein reagents requires substantial investment of time, expertise, equipment, and infrastructure. As a result, this significantly limits the availability...

Inventor(s): Andrew Ellington, Sanchita Bhadra, Arti Pothukuchy, Michelle Byrom, Raghav Shroff, Jared Ellefson, Jimmy Gollihar | Published: 11/1/2023

Category(s): Life sciences > Research tools > Reagent, Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Therapeutics > Synthetic biology

Keyword(s): Diagnostics, Isothermal amplification, Nucleic acid amplification, Point-of-need

Br512: an improved DNA polymerase for isothermal amplification assays

Unmet need Loop-mediated isothermal amplification (LAMP) is a technique that allows for nucleic acid amplification without the need for a thermocycler. This technology enables testing for infections practically anywhere. Testing shortages have exacerbated the COVID-19 pandemic, and there is a high demand for tests that can provide rapid results outside...

Inventor(s): Andrew Ellington, Andre Maranhao, Sanchita Bhadra | Published: 11/1/2023

Category(s): Life sciences > Research tools > Reagent

Keyword(s): COVID-19, Diagnostics, Engineered enzyme, Isothermal amplification, LAMP, Nucleic acid amplification, Point-of-care, Point-of-need, Polymerase