|
2-photon endoscopic fluorescence probe for advanced medical imaging
Background/problem
Existing approaches to tissue imaging, particularly for early cancer detection, face several significant challenges. Techniques such as MRI and PET provide functional information but lack the cellular-level resolution needed for early diagnosis and involve contrast agents and radiation exposure. Two-photon (2P) fluorescence imaging...
|
|
Efficient MR fingerprinting using B-splines to improve (quantitative) MRI
Background/problem
Magnetic resonance imaging (MRI) is a state-of-the-art diagnostic imaging modality which beneficially features excellent soft tissue contrast and lacks use of ionizing radiation. In clinical practice, MRI generates contrast-weighted images based on the intrinsic tissue parameters of the subject, which are then interpreted by a radiologist....
|
|
Deep learning for rapid and robust fluorescence lifetime imaging
Deep-learning approach has the potential to unlock fluorescent lifetime imaging for clinical applications. Fluorescence lifetime imaging microscopy (FLIM) is a widely used tool for biomedical imaging that offers many unique advantages over typical intensity-based fluorescence microscopy. FLIM is advancing fundamental biological research by enabling...
|
|
Colloidal building technique for higher order materials
Background
Radiation pressure, or radiation force, is produced by the electromagnetic interaction between light and a small particle, which is polarized by light. This interaction is the driving force behind the optical trapping of small particles. Tools based on optical trapping and manipulation are called “optical tweezers.” Since the...
|
|
Moiré chiral metamaterials and their application on label-free enantiodiscrimination of drug molecules
Real-time analytical device enables continuous manufacturing of pharmaceutical ingredients Description Pharmaceutical drugs are typically made in large batches with multi-step processes. A typical batch manufacturing facility contains multiple pieces of complicated equipment and can require an investment of billions of dollars. Batch manufacturing processes...
|
