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Multi-material electrospinning system for 3D-printed fiber architectures
Background
Electrospinning and additive manufacturing have become increasingly important in fields such as biotechnology, pharmaceuticals, and tissue engineering, where there is growing demand for complex fiber architectures and multifunctional material systems. However, traditional electrospinning methods struggle to meet the precision, scalability,...
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Mopill: solar-powered mobile 3D printing system for on-demand drug manufacturing
Background
Pharmaceutical manufacturing has long relied on centralized, large-scale batch production that demands substantial infrastructure and stable energy sources. However, this model is increasingly ill-suited for the growing need for personalized, rapidly deployable medications, especially in disaster relief zones, rural areas, or low-resource...
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Lipid-coated granule feedstock for high-precision pharmaceutical 3D printing
Background
The field of pharmaceutical manufacturing is rapidly evolving to meet increasing demands for personalized drug delivery, precise dosage forms, and consistent controlled-release profiles. As healthcare shifts toward individualized treatment plans, clinicians and researchers are seeking advanced manufacturing solutions that deliver compact,...
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Scalable artificial tissue engineering for tunable 3D structures and selective membranes
This invention uses a scalable droplet interface bilayer method to create customizable artificial tissues from water droplets. The tissues are tunable for conductivity, stiffness, and self-healing, enabling applications like 3D bioprinting and selective electrically driven separations.
Background
The field of tissue engineering has long sought to...
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Pharmaceutical manufacturing of the future: a continuous 3D printing approach for personalized medicine
Background
Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharmaceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
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Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications.
Background
Producing micro- and nanoparticles for pharmaceutical and...
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Enhanced pharmaceutical co-crystal production via continuous dielectric heating and hot melt extrusion method
CoMIDEx uses microwave heating and extrusion to create drug cocrystals, enhancing their solubility and effectiveness. It’s a continuous, eco-friendly process that improves medicine availability without using solvents.
Background
Pharmaceutical development heavily relies on active pharmaceutical ingredients (APIs) to provide therapeutic benefits....
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Optimized inhalation formulation of clofazimine and amikacin for targeted treatment of respiratory infections
The invention describes a pharmaceutical composition combining clofazimine and amikacin for inhalation to treat respiratory diseases like tuberculosis. This formulation enhances drug delivery to the lungs, improving efficacy and reducing systemic side effects.
Background
Bacterial infections, particularly those caused by mycobacteria such as Mycobacterium...
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Recognitive biodegradable nanoparticles for targeted in vivo diagnostics and therapeutics
Recognitive biodegradable nanoparticles combine molecularly imprinted polymers with biodegradable cores to detect specific target molecules like proteins for in vivo diagnostics. They offer high affinity, selectivity, lower production costs, and reduced immunologic response.
Background
The field of molecularly imprinted polymers (MIPs) involves creating...
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3D printing technology for customized pharmaceutical dosage forms
The invention utilizes 3D printing with selective laser sintering to create pharmaceutical tablets from amorphous solid dispersions, enhancing drug solubility and bioavailability without additional excipients, allowing customizable drug release rates and unique dosage forms.
Background
In the pharmaceutical industry, the development of drugs with...
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