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A Smartwatch-integrable, non-invasive RF bioimpedance wearable system for continuous, equitable blood pressure monitoring
This technology is a smartwatch-compatible, low-power wearable that uses radio frequency bioimpedance and AI to continuously and non-invasively monitor blood pressure, offering accurate, skin color-independent readings and robust performance compared to traditional optical sensors.
Background
Blood pressure (BP) monitoring is a cornerstone of cardiovascular...
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A Magnetically Steerable Guidewire for Neuro-Endovascular Intervention
Background
Neuro-endovascular intervention for acute ischemic stroke caused by large vessel occlusion relies on precise guidewire navigation through narrow, tortuous, and fragile cerebral vessels to perform mechanical thrombectomy (MT). Although MT has become the gold standard for restoring blood flow, navigating to the clot is technically demanding...
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Fully Wearable Band for Long-Term Peripheral Ultrasound Neuromodulation in Pain Management
Wearable ultrasound neuromodulation device for peripheral nerve pain relief
A wearable ultrasound armband uses a focused piezoelectric transducer and acoustic hydrogel to deliver low-intensity ultrasound pulses to peripheral nerves, noninvasively reducing chronic and neuropathic pain for several hours.
Background
Peripheral nerve stimulation has...
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Drug-eluting Tubes for Improved Patient Care
Drug-Eluting Porous Polymer Tubes for Sustained Local Therapeutic Delivery in Medical Devices
A porous polyethylene chest tube releases pain medication locally for up to two weeks after thoracic surgery, enhancing pain management while maintaining the flexibility and functionality of standard tubes.
Background
Effective pain management is crucial...
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Ultrasound-triggered anesthetic drug delivery for on-demand chronic pain management
A nanoparticle-based ultrasound-responsive drug delivery system for precise, controlled, and targeted therapeutic release
This technology uses ultrasound-triggered nanoparticles to deliver local anesthetics precisely and safely for pain management, reducing side effects and opioid risks, with potential for targeted delivery of other drugs in cancer,...
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Wearable electronic tattoo for real-time hydration monitoring
Background
Accurate hydration assessment is essential for maintaining health, performance, and safety; even mild dehydration can impair cognition, physical function, and cardiovascular stability. Populations such as older adults, athletes, outdoor laborers, military personnel, and individuals with limited access to clinical care are particularly...
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Wearable ultrasound and EEG patch for noninvasive REM sleep enhancement
Background
Sleep is essential for emotional regulation, cognitive function, and overall health. Chronic sleep disruption, prevalent among individuals with PTSD, shift workers, and military personnel, affects tens of millions and contributes to serious long-term health consequences. Despite growing awareness, most existing sleep aid technologies fail...
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Microfluidic evaporator concentrator for increasing analyte concentration in small-volume aqueous samples
Background
Point-of-care diagnostics, environmental monitoring, and biomanufacturing increasingly require the detection of low concentrations of biomolecules and other non-volatile analytes in aqueous samples, yet many portable analytical systems lack sufficient sensitivity without a preconcentration step.
Existing methods such as centrifugal evaporation,...
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Dual-stiffness passive prosthetic ankle for direction-dependent stability
Background
Lower-limb amputees often struggle to maintain balance and stability during everyday activities, particularly when turning or navigating uneven surfaces, because the loss of natural ankle musculature and proprioception limits their ability to adapt to changing loads and directions. Most prosthetic ankles provide a single fixed stiffness,...
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Real-time optical microdialysis sensor for continuous metabolite monitoring
Background
Continuous, real-time monitoring of small molecule metabolites in living tissue is critical for managing conditions like traumatic brain injury (TBI), where rapid shifts in metabolism can precede clinical deterioration. Traditional methods such as microdialysis allow for extracellular fluid sampling of metabolites like glucose, lactate,...
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