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Solutions for endotracheal tube (ETT) management in ICU patients
Background/problem
Patients in the Intensive Care Unit (ICU) often require prolonged mechanical ventilation via an Endotracheal Tube (ETT). The ETT must be correctly positioned in the trachea and secured to prevent migration. However, factors such as patient movement, oral/nasal secretions, and adhesive deterioration often lead to ETT malpositioning....
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Mechanical conditioning for mesenchymal stem cell rejuvenation
This technology uses mechanical force to rejuvenate aged stem cells. It enhances cell function, reduces aging markers, and improves DNA repair, making the cells more suitable for regenerative therapies.
Background
Mesenchymal stem cells (MSCs) hold immense promise for regenerative medicine due to their availability, multipotency, and immunomodulatory...
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Tactile sensing technology for enhanced object morphology detection and classification using machine learning
A four-dimensional tactile sensing system uses a camera and tactile sensors to measure an object’s shape and stiffness. It employs machine learning for object classification, with potential applications in medical diagnostics and other fields requiring detailed tactile feedback.
Background
Tactile sensing technology has become increasingly significant...
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Adaptable robotic gait trainer for rehabilitation
The adaptable robotic gait trainer is a cost-effective rehabilitation device that uses a single motor and adjustable linkages to assist individuals with gait impairments. It customizes gait patterns, monitors user movement, and supports body weight, enhancing accessibility in healthcare settings.
Background
Gait impairments, often resulting from neurological...
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Nanodelivery systems for long-term controlled release of pharmaceuticals
This invention describes a nanodelivery system for controlled drug release using biocompatible materials. It features implantable or injectable devices with precise aperture control for zero-order kinetics, ensuring consistent therapeutic delivery over extended periods of time.
Background
Implantable drug delivery systems offer significant advantages...
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Nitrogen-doped graphene-rich carbon materials for technological applications
This invention describes a low-temperature pyrolysis method to produce graphene-rich carbon materials using hexagonal metal oxides as templates. The process prevents graphene stacking into graphite and allows nitrogen doping, enhancing properties for applications like electrodes and catalysts.
Background
Graphene, a single layer of carbon atoms arranged...
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Individualized intranasal delivery system for direct pharmaceutical administration to the brain
The technology involves a customizable nasal delivery device for precise administration of medications directly to the brain, bypassing traditional barriers. It uses imaging techniques for optimal placement, enhancing drug delivery efficiency and minimizing systemic side effects.
Background
Oral administration remains the predominant method for drug...
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Blood pressure regulation via thermal control during sleep
This technology uses a stimulating device and blood pressure monitor to regulate blood flow and lower blood pressure during sleep through targeted thermal stimulation, promoting cardiovascular health by integrating into a climate-controlled bed.
Background
High blood pressure, or hypertension, is a significant health concern linked to various cardiovascular...
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Flexible heat exchange pad for enhanced thermal therapy and skin temperature control
The heat exchange pad is a flexible, 3D-printed device designed to control skin temperature by circulating fluid through microchannels that mimic the vascular network of glabrous skin, enhancing heat transfer efficiency and conforming to patient anatomy.
Background
Managing body temperature effectively is crucial in various medical scenarios, such...
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Biomimetic vascularized platforms for tissue engineering applications
Microfluidic vascularized platforms simulate biological environments for tissue engineering by creating 3D models with vascular networks. These platforms use polymers and hydrogels to study cell interactions, transport phenomena, and drug effects, enhancing physiological relevance over traditional cultures.
Background
Microfluidic technology is a...
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