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Fluorescence lifetime imaging for retinal function assessment
This invention uses a laser-based imaging system to study the eye’s retina. By measuring light responses, it provides insights into retinal health and potential diseases like age-related macular degeneration.
Background
Two-photon excited fluorescence (TPEF) is a powerful technique used to study the eye. TPEF allows researchers to excite intrinsic...
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High-speed, high-precision, deep-tissue three-dimensional single-particle tracking
The invention enhances particle tracking in biological research using spatiotemporal offset light beams with two-photon microscopy. It achieves high-speed, precise, deep tissue tracking, offering improved penetration depth and temporal resolution for studying molecular processes.
Background
Single-particle tracking (SPT) is a powerful tool for...
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Quad-view image splitter for multicolor fluorescence microscopy
Background/problem
Multicolor fluorescence microscopy is an important tool in biological research, enabling scientists to observe various components of living cells using fluorescent dyes that emit light at different wavelengths. This technique offers valuable insights into cellular structures and functions, advancing our knowledge of complex biological...
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Deep learning for rapid and robust fluorescence lifetime imaging
Deep-learning approach has the potential to unlock fluorescent lifetime imaging for clinical applications. Fluorescence lifetime imaging microscopy (FLIM) is a widely used tool for biomedical imaging that offers many unique advantages over typical intensity-based fluorescence microscopy. FLIM is advancing fundamental biological research by enabling...
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